Pharmacology

Introduction

Department of Pharmacology has been updated with well-equipped infrastructure and is engaged in the teaching programme of MBBS, B.Sc. (Hons) Nursing. It has also started its Post graduate course in Pharmacology from Jan-2019 session.

Under the pharmacovigilance program of India (PVPI), Adverse Drug Reaction (ADR) monitoring centre is functional at department of pharmacology, AIIMS Patna. The Adverse Drug Reaction Monitoring Centre forwards the adverse drug reaction (ADR) data to national Adverse Drug Reaction Monitoring centre.

To cater 'patient care needs' a Therapeutic Drug Monitoring Lab (TDM) is being established and in process of standardization. For the 'animal research needs' of the institute, a Central Animal House is also being established. The department envisages starting PhD and super specialty courses DM (Clinical Pharmacology). The department is also engaged in constantly upgrading education, research and patient care capacities.

Computer-based practical classes are being carried out. We have completely phased out animal experimentation at the UG level and are actively teaching experimental pharmacology using virtual simulation software Ex-Pharm Pro and established Computer Assisted Lab (CAL). The department has also phased out the conventional pharmacy practical exercises with Clinical pharmacy.

Problem based learning, drug interactions, fixed dose combinations and causality assessment of adverse drug reactions, prescription audit and analysis training have become a part of the curriculum of pharmacology practical classes.

  • The department is well equipped with CAL Lab, Therapeutic Drug Monitoring Lab, PG Research lab with Flowcytometer & HPLC.
  • The department is running ADR monitoring centre under Pharmacovigilance programme of India (PvPI), to report ADRs due to drugs from OPD & IPD patients. It is also in the process of planning to educate the patients about adverse drug reactions, and how to report them for safe use of medicines.
  • In upcoming days, department is planning on regular basis to conduct a workshop/CME to train and involve Faculties, junior doctors, nurses, nursing students and other paramedics in ADR reporting under PvPI to improve the number and quantity of ADR reporting.
  • The department will further set up a Clinical Pharmacology Unit (CPU) in the hospital building to cater to the patient care and clinical research activities.
  • The department is in process of developing and providing best possible pharmacotherapeutic support to various departments of the institute in form of prescription audit system; e-prescription system to detect drug-drug interactions and adverse drug reactions. There is a geriatric and paediatric Clinical Pharmacology Unit in the hospital, pharmacogenomic and toxicology lab for prevention, early detection and management of ADRs; drug testing lab for quality check of medicines, besides other clinical services will begin in due course of time.
Future planning
  • Future aim of the department is to establish “Central Animal House” and make it functional for teaching and research purposes of PG students and Faculty members of the institute, which could benefit in research of the students as well as faculty members.
  • To start “Drug And Poison Information Centre” that shall work as an operational unit which will provide up-to-date scientific and technical information on drugs and poisoning.
  • Clinical Pharmacology Unit (CPU) will be set up in the upcoming hospital building so that DM clinical Pharmacology may be started, it is also planning to establish a Drug Museum for better understanding of pharmacology.

  • With the department's effort Institute animal house construction is completed. The required equipment and staff is under process of procurement. An Institutional ‘Animal Ethic Committee’ is being formed and to get CPCSEA registration is also under process, this will ensure that animal based research activities may be started soon.
  • After successful establishment and test-run of Computer Assisted Lab (CAL), the department has started clinical pharmacy lab with ‘mannequin and clinically used devices’ of simulation exercises for MBBS and B.Sc. (Hons.) nursing students.
  • The (ADR) Adverse Drug Reaction monitoring centre (AMC) has been set up with the Director’s concurrence and as an essential part of Pharmacovigilance Programme of India (PvPI) under the aegis of ministry of Health and Family Welfare, Government of India.
  • ADR Monitoring and Reporting under the Pharmacovigilance Programme of India is being done regularly, the IPC has also provided one TA to assist in the work of regular reporting since February 2015.
  • ADR monitoring centre, AIIMS Patna has reported a total no. of 302 suspected cases to National Coordinating Centre, IPC Ghaziabad during the period of April 2020 to March 2021.
  • AIIMS Patna is designated as one of the Medical Device Adverse Event Monitoring Centre (MDMC) w.e.f. 31st July, 2019 with the concurrence of Director and as part of Materiovigilance Programme of India (MvPI) under the aegis of ministry of Health and Family Welfare, , Government of India.
  • MDMC, AIIMS Patna has received and collected a total no. of 77 suspected adverse event related to medical device from April 2020 to March 2021 from different departments & wards and have been sent to National Coordinating Centre, IPC Ghaziabad.
  • Department is also running awareness programme for paramedical staffs of AIIMS hospital and organises CME/Workshop on ADR monitoring programme for junior & senior residents, faculty etc. for better participation and reporting of adverse drug reactions in this region.
Teaching and training
MBBS
  • The teaching and learning methodology of department include both conventional as well as modern methods. It includes didactic lecture and practical classes. Computer-based practical classes are being conducted.
  • The department has completely phased out ‘animal experimentation’ at the UG level and is actively teaching experimental pharmacology using virtual simulation software – Ex Pharm Pro. (CAL lab.)
  • Department also conducts a software based online exam of experimental pharmacology, this is the first time in Bihar that such an exam has been conducted.
  • Clinical pharmacology exercises (Clinical case follow up, testing of analgesic activity and psychomotor function alteration by drugs, on human volunteers) for the new batch (2020 batch) are being planned and will be started from 4th semester (January 2022).
  • Problem based learning has been initiated for both, old and new batch. Drug interactions, fixed dose combinations and causality assessment of adverse drug reactions are being taught to the students, both in lectures and in practicals. Prescription audit and analysis training has been started since 3rd semester (Batch 2013).
  • Mannequin based simulation to reinforce Pharmacological concept has been started for MBBS and B.Sc. (Hons.) nursing students.
B.Sc. (Hons.) Nursing
  • Lectures and tutorial classes are held regularly. We are teaching the nurses about clinical aspect of pharmacology as well their responsibility towards patients.
  • Mannequin based simulation to reinforce pharmacological concept has been started.
Short term (12 to 24 months) training
  • Optimal training of the in-house staff is being carried out for teaching and research activities to start clinical services.
  • Basic research related equipment and basic clinical services related equipment procurement is under process.
Long term (2 to 5 years) training
  • Clinical Pharmacology Unit (CPU) is in process of standardizing available ‘equipment and processes’ with on-going validation procdeures, to start clinical trials.
  • Regular training activities will be conducted for capacity building.
Community services/ Outreach programme
  • The faculty members of the institute involve themselves in medical camps of community outreach health programme of the department of telemedicine, AIIMS Patna.

SL No.Name of FacultyDesignation
1.Dr. Pramod Kumar ManjhiAssistant Professor & Head
2.Dr. Shruti SinghAssistant Professor
3.Dr. Rajesh Kumar MeenaAssistant Professor
4.Dr. Sunil Kumar SinghAssistant Professor

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